Impact on Reactivity

The inductive effect influences reactivity and acidity/basicity of organic compounds as follows:

1. Reactivity:
- +I effect increases electron density, enhancing nucleophilicity
- -I effect decreases electron density, enhancing electrophilicity

2. Acidity:
- -I effect increases acidity by stabilizing the conjugate base
- +I effect decreases acidity by destabilizing the conjugate base

3. Basicity:
- +I effect increases basicity by increasing electron density
- -I effect decreases basicity by decreasing electron density