Anaphase promoting complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur?
(c) If anaphase promoting complex is defective in a human cell, the chromosomes will not segregate during anaphase of mitosis. APC triggers the transition from metaphase to anaphase by tagging specific proteins for degradation.
Concept Enhancer:
Anaphase stage of mitosis is characterised by two events
(a) Splitting of centromeres and segregation of chromosomes
(b) Movement of chromatids towards the opposite poles.