NEET Practice Questions (MCQs) with Answers & Solutions

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Adolescence is identified as a critical period for initiating habits such as smoking, drug, or alcohol use. Why is this age particularly susceptible?

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Explanation

The text mentions: 'It is also true that habits such as smoking, taking drug or alcohol are more likely to be taken up at a young age, more during adolescence.' The broader context discusses curiosity, experimentation, peer pressure, and stress as motivators during this phase, highlighting psychological vulnerability and peer influence.

What happens if an abuser is unable to get money to buy drugs/alcohol as described in the text?

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Explanation

The text states: 'If an abuser is unable to get money to buy drugs/alcohol he/she may turn to stealing.'

The adverse effects of drug/alcohol abuse are not restricted to the person using the substances. To whom else can it cause mental and financial distress?

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Explanation

The text clearly states: 'At times, a drug/alcohol addict becomes the cause of mental and financial distress to his/her entire family and friends.'

What key processes are involved in 'downstream processing' after the biosynthetic stage in biotechnology?

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Explanation

According to the NCERT text, 'After completion of the biosynthetic stage, the product has to be subjected through a series of processes... The processes include separation and purification, which are collectively referred to as downstream processing.'

Which of the following is NOT typically a component of downstream processing?

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Explanation

Downstream processing occurs after the biosynthetic stage. The biosynthetic stage, where the product is actually made in a bioreactor, precedes downstream processing. Quality control, formulation, and potentially clinical trials are part of making the product ready for marketing, which falls under the broader scope of downstream processing activities.

The ultimate goal of downstream processing is to make the product ready for:

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Explanation

The NCERT states, 'After completion of the biosynthetic stage, the product has to be subjected through a series of processes before it is ready for marketing as a finished active product.' This highlights the end goal of downstream processing.

Consider the following steps: (i) Separation; (ii) Purification; (iii) Biosynthesis; (iv) Quality control. Which steps are collectively referred to as Downstream Processing?

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Explanation

The NCERT explicitly states that separation and purification are part of downstream processing. While not explicitly mentioned as 'downstream processing' within the provided snippet, the summary states 'purification of the gene product, i.e., the functional protein and finally making a suitable formulation for marketing.' Formulation and marketing readiness imply quality control. Biosynthesis (iii) is the preceding stage.

Why is downstream processing a crucial step in biotechnological production?

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Explanation

Downstream processing involves separation and purification, which are essential to isolate the desired product from the cell culture, remove impurities, and prepare it for its intended use or marketing. This makes the product 'ready for marketing as a finished active product' as per the NCERT text.

Which of the following activities is NOT a primary concern during the biosynthetic stage that precedes downstream processing?

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Explanation

Removing contaminants from the final product is a key function of downstream processing. The biosynthetic stage focuses on producing the product effectively, for example, by providing 'optimum growth conditions (temperature, pH, substrate, salts, vitamins, oxygen)' and using bioreactors for 'large yield of desired protein'.

If a protein therapeutic is produced using recombinant DNA technology, what stage follows the production of the protein in the host cells?

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Explanation

The NCERT summary outlines the sequence: 'expression of the foreign gene... purification of the gene product, i.e., the functional protein and finally making a suitable formulation for marketing.' The purification and formulation steps constitute downstream processing, which follows the expression (production) of the protein.

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