Consider the following statements regarding protein denaturation:
I. The overall folding of the polypeptide chain is affected.
II. The sequence of amino acids changes.
III. Intermolecular hydrogen bonds are strengthened.
Which of the statements is/are correct?
I is correct because 'globules unfold and helix get uncoiled' affecting overall folding (tertiary and secondary structures). II is incorrect because the primary structure (amino acid sequence) remains intact. III is incorrect because hydrogen bonds are 'disturbed', not strengthened.