NEET Practice Questions (MCQs) with Answers & Solutions

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Transgenic animals are made more sensitive to toxic substances for which specific application?

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Explanation

The text mentions, 'Transgenic animals are made that carry genes which make them more sensitive to toxic substances than non-transgenic animals. They are then exposed to the toxic substances and the effects studied. Toxicity testing in such animals will allow us to obtain results in less time.'

For which of the following human diseases are transgenic models currently available, according to the NCERT text?

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Explanation

The NCERT states, 'Today transgenic models exist for many human diseases such as cancer, cystic fibrosis, rheumatoid arthritis and Alzheimer’s.'

The production of human $\alpha$-1-antitrypsin by transgenic animals is an effort to treat which human ailment?

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Explanation

As per the text, 'Transgenic animals that produce useful biological products can be created by the introduction of the portion of DNA (or genes) which codes for a particular product such as human protein ($\alpha$-1-antitrypsin) used to treat emphysema.'

Which of the following is NOT a common reason for producing transgenic animals?

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Explanation

The NCERT outlines reasons such as 'Normal physiology and development', 'Study of disease', 'Biological products', 'Vaccine safety', and 'Chemical safety testing'. Increasing genetic diversity in a wild population is not listed as a direct goal for producing transgenic animals.

In the context of vaccine safety testing, which animal could potentially be replaced by transgenic mice if the latter are found reliable?

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Explanation

The text states, 'Transgenic mice are being used to test the safety of the polio vaccine. If successful and found to be reliable, they could replace the use of monkeys to test the safety of batches of the vaccine.'

Ethical issues surrounding genetic modification of organisms primarily arise due to:

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Explanation

The NCERT mentions, 'Genetic modification of organisms can have unpredictable results when such organisms are introduced into the ecosystem.' It also highlights the need for regulation to evaluate the 'morality of all human activities that might help or harm living organisms.'

The primary objective of developing transgenic animals for 'Normal physiology and development' studies is to:

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Explanation

The NCERT elaborates, 'Transgenic animals can be specifically designed to allow the study of how genes are regulated, and how they affect the normal functions of the body and its development, e.g., study of complex factors involved in growth such as insulin-like growth factor.'

What characteristic makes human alpha-lactalbumin in Rosie's milk nutritionally more balanced for human babies than natural cow milk?

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Explanation

The NCERT text states, 'The milk contained the human alpha-lactalbumin and was nutritionally a more balanced product for human babies than natural cow-milk.' The key phrase here is 'human protein-enriched'.

Which of the following processes is directly responsible for creating a proton gradient across the thylakoid membrane during the light reaction?

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Explanation

According to the NCERT text, 'Splitting of water molecules is associated with PS II resulting in the release of O2, protons and transfer of electrons to PS II.' The release of protons ($H^+$) into the thylakoid lumen directly contributes to the proton gradient.

What is the primary role of the F0 part of the ATPase enzyme in chemiosmosis?

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Explanation

The NCERT states, 'The breakdown of the protons gradient due to movement through the F0 part of the ATPase enzyme releases enough energy for synthesis of ATP.' The F0 part functions as the transmembrane channel allowing protons to flow down their electrochemical gradient.

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