NEET Practice Questions (MCQs) with Answers & Solutions

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The primary reason lipids are found in the acid-insoluble fraction, despite not being strictly macromolecules, is because:

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Explanation

The text explains: 'Cell membrane and other membranes are broken into pieces, and form vesicles which are not water soluble. Therefore, these membrane fragments in the form of vesicles get separated along with the acid insoluble pool and hence in the macromolecular fraction. Lipids are not strictly macromolecules.'

Which of the following describes the chemical composition of a nucleotide?

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Explanation

According to the NCERT text, 'Nucleic acids are the polymers of nucleotides which in turn consist of a base, a pentose sugar and phosphate moiety.' Additionally, another section states, 'A nucleotide has three chemically distinct components. One is a heterocyclic compound, the second is a monosaccharide and the third a phosphoric acid or phosphate.'

In DNA, the sugar moiety is $\beta$-D-2-deoxyribose. What is the corresponding sugar in RNA?

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Explanation

The NCERT text states, 'DNA contains a five carbon sugar molecule called 2-deoxyribose whereas RNA contains ribose.' More specifically, 'In DNA molecules, the sugar moiety is $\beta$-D-2-deoxyribose whereas in RNA molecule, it is $\beta$-D-ribose.'

Which of the following bases is exclusive to RNA and replaces thymine found in DNA?

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Explanation

The NCERT text clearly states, 'RNA also contains four bases, the first three bases are same as in DNA but the fourth one is uracil (U).' It further adds, 'The fourth base is thymine in DNA and uracil in RNA.'

A nucleoside is formed by the attachment of a base to which position of the sugar?

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Explanation

The NCERT states, 'A unit formed by the attachment of a base to 1¢ position of sugar is known as nucleoside.' Another part specifies: 'A nitrogenous base is linked to the OH of 1' C pentose sugar through a N-glycosidic linkage to form a nucleoside.'

Nucleotides are linked together by which type of bond to form a nucleic acid chain?

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Explanation

The NCERT text mentions, 'Nucleotides are joined together by phosphodiester linkage between 5¢ and 3 carbon atoms of the pentose sugar.'

According to Chargaff's rule for double-stranded DNA, which of the following ratios is constant and equals one?

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Explanation

The NCERT text states, 'this proposition was also based on the observation of Erwin Chargaff that for a double stranded DNA, the ratios between Adenine and Thymine and Guanine and Cytosine are constant and equals one.'

What is the primary function of DNA in the cell?

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Explanation

The NCERT text explicitly states, 'DNA is the chemical basis of heredity and have the coded message for proteins to be synthesised in the cell.'

Identify the type of nitrogenous base that classifies Adenine and Guanine.

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Explanation

The NCERT text states, 'There are two types of nitrogenous bases – Purines (Adenine and Guanine), and Pyrimidines (Cytosine, Uracil and Thymine).Adenine and Guanine are substituted purines while the rest are substituted pyrimidines.'

In the double helix structure of DNA, where are the hydrogen bonds formed?

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Explanation

The NCERT text describes, 'Two nucleic acid chains are wound about each other and held together by hydrogen bonds between pairs of bases.' It further clarifies, 'Adenine forms hydrogen bonds with thymine whereas cytosine forms hydrogen bonds with guanine.'

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