Which of the following is the first step of glycolysis (C.P.M.T. 2004)
The first step of glycolysis is the phosphorylation of glucose. During this step, a phosphate group is added to glucose to form glucose-6-phosphate. This reaction is catalyzed by the enzyme hexokinase and is crucial for trapping glucose in the cell and making it more chemically reactive for subsequent steps in glycolysis.