NEET Practice Questions (MCQs) with Answers & Solutions

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The statement 'Downstream processing technologies to purify the protein/organic compound' highlights its role in which of the critical research areas of biotechnology?

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Explanation

The NCERT text lists 'Downstream processing technologies to purify the protein/organic compound' as one of the three critical research areas, directly relating it to purification. Formulation is implied in the overall goal of making a packaged product ready for marketing.

Which of the following is an INCORRECT statement regarding Downstream Processing?

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Explanation

Downstream processing occurs after the biosynthetic stage, as stated in the text: 'After completion of the biosynthetic stage, the product has to be subjected through a series of processes...'

If a genetically modified organism produces a therapeutic protein in a bioreactor, what immediately follows the harvest of the culture broth for product recovery?

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Explanation

After the growth and production in the bioreactor (biosynthetic stage), the next set of operations for product recovery and preparation for marketing is Downstream Processing.

The processes involved in making a product ready for marketing, which includes separation and purification, are a part of:

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Explanation

The NCERT clearly defines Downstream Processing as the series of processes, including separation and purification, that occur after biosynthesis to make the product ready for marketing.

Which of the following statements BEST defines an amphibolic pathway?

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Explanation

The NCERT text states: 'The respiratory pathway is an amphibolic pathway as it involves both anabolism and catabolism.' This clearly defines an amphibolic pathway as one that participates in both constructive and destructive metabolic processes.

The respiratory pathway is considered amphibolic because:

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Explanation

The NCERT states, 'Since respiration involves breakdown of substrates, the respiratory process has traditionally been considered a catabolic process... But... it is these very compounds that would be withdrawn from the respiratory pathway for the synthesis of the said substrates.' This dual role of breaking down substrates and providing precursors for synthesis makes it amphibolic.

If fatty acids are to be utilized as a respiratory substrate, they are first degraded to:

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Explanation

The NCERT text mentions: 'Fats would need to be broken down into glycerol and fatty acids first. If fatty acids were to be respired they would first be degraded to acetyl CoA and enter the pathway.'

Glycerol, when used as a respiratory substrate, enters the pathway after being converted to:

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Explanation

The NCERT states: 'Glycerol would enter the pathway after being converted to PGAL.'

Proteins, after degradation by proteases and deamination, can enter the respiratory pathway as:

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Explanation

According to the NCERT: 'The proteins would be degraded by proteases and the individual amino acids (after deamination) depending on their structure would enter the pathway at some stage within the Krebs’ cycle or even as pyruvate or acetyl CoA.'

Which of the following is an example of an anabolic process within the respiratory pathway?

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Explanation

Anabolism refers to synthesis. While the respiratory pathway primarily involves catabolic breakdown for energy, intermediates can be 'withdrawn from the respiratory pathway for the synthesis of the said substrates,' such as fats, which is an anabolic process.

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