A diploid cell in G1 phase has '2n' chromosomes and '2C' DNA content. What will be the number of chromosomes and DNA content respectively in the same cell at the end of M phase?
During the S phase, DNA replication occurs, so the DNA content doubles from 2C to 4C, but the chromosome number remains 2n because sister chromatids are still joined. In M phase (mitosis), the sister chromatids separate and are distributed to daughter cells. Therefore, each daughter cell (and thus the cell at the end of M phase) will have 2n chromosomes and 2C DNA content, identical to the parent cell in G1. Mitosis is an equational division where the chromosome number in parent and progeny cells remains the same.