Biomolecules MCQs for NEET — Zoology Questions with Answers

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NEET 2023

Statement I: Low temperature preserves the enzyme in a temporarily inactive state whereas high temperature destroys enzymatic activity because proteins are denatured by heat. Statement II: When the inhibitor closely resembles the substrate in its molecular structure and inhibits the activity of the enzyme, it is known as competitive inhibitor.

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Explanation

Standard NCERT facts; both true.

NEET 2023

Statement I: A protein is imagined as a line, the left end represented by first amino acid (C-terminal) and the right end represented by last amino acid (N-terminal). Statement II: Adult human haemoglobin consists of 4 subunits (two subunits of α type and two subunits of β type).

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Explanation

I wrong (left = N-terminal, right = C-terminal). II correct (HbA = α₂β₂).

NEET 2024

Match List I with List II:

List I List II
A. Lipase I. Peptide bond
B. Nuclease II. Ester bond
C. Protease III. Glycosidic bond
D. Amylase IV. Phosphodiester bond

Choose the correct answer from the options given below:

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Explanation

Lipase — ester; Nuclease — phosphodiester; Protease — peptide; Amylase — glycosidic.

NEET 2024

Regarding catalytic cycle of an enzyme action, select the correct sequential steps:

A. Substrate enzyme complex formation. B. Free enzyme ready to bind with another substrate. C. Release of products. D. Chemical bonds of the substrate broken. E. Substrate binding to active site.

Choose the correct answer from the options given below:

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Explanation

Binding (E) → ES complex (A) → bond cleavage (D) → product release (C) → free enzyme (B).

NEET 2025

Name the class of enzyme that usually catalyzes the following reaction: $S–G + S^\# \to S + S^\#–G$. Where, $G$ → a group other than hydrogen, $S$ → a substrate, $S^\#$ → another substrate.

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Explanation

Transfer of a chemical group $G$ (other than H) from one substrate to another is catalysed by transferases.

NEET 2025

Which one of the following enzymes contains 'Haem' as the prosthetic group?

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Explanation

Catalase is a haem-containing enzyme (the prosthetic group is haem). Carbonic anhydrase uses zinc, and succinate dehydrogenase uses FAD/Fe-S clusters.

NEET 2025

Match List I with List II:

List I — A. Adenosine, B. Adenylic acid, C. Adenine, D. Alanine

List II — I. Nitrogen base, II. Nucleotide, III. Nucleoside, IV. Amino acid

Choose the option with all correct matches:

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Explanation

Adenosine = nucleoside (III); Adenylic acid (AMP) = nucleotide (II); Adenine = nitrogen base (I); Alanine = amino acid (IV).

NEET 2025

The protein portion of an enzyme is called:

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Explanation

The protein part of a conjugate enzyme is the apoenzyme; apoenzyme + cofactor = holoenzyme.

NEET 2025

Why can't insulin be given orally to diabetic patients?

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Explanation

Insulin is a protein; if taken orally it would be digested by proteases in the GI tract, so it must be injected.

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