Molecular Basis of Inheritance MCQs for NEET — Botany Questions with Answers

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Which of the following statements about repetitive DNA in DNA fingerprinting is INCORRECT?

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Explanation

According to the NCERT text, 'These sequences normally do not code for any proteins, but they form a large portion of human genome.' Therefore, option o2 is incorrect.

What percentage of base sequences among humans is considered the same, as per the context provided for DNA fingerprinting?

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Explanation

The NCERT text states: 'As stated in the preceding section, 99.9 per cent of base sequence among humans is the same.'

The technique of DNA fingerprinting was initially developed by:

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Explanation

The NCERT text explicitly mentions: 'The technique of DNA Fingerprinting was initially developed by Alec Jeffreys.'

VNTR (Variable Number of Tandem Repeats) used by Alec Jeffreys belongs to which class of satellite DNA?

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Explanation

The NCERT text states: 'The VNTR belongs to a class of satellite DNA referred to as mini-satellite.'

Which of the following is NOT a step in the DNA fingerprinting technique, as described in the provided context?

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Explanation

The context describes 'Souther n blot hybridisation using radiolabelled VNTR as a probe' and lists steps including isolation, digestion, separation, transferring, hybridisation, and detection. PCR amplification is not mentioned as part of the described technique.

What is the primary reason that DNA from any tissue (e.g., blood, hair follicle, skin) from an individual is suitable for DNA fingerprinting?

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Explanation

The NCERT text clearly states: 'Since DNA from every tissue (such as blood, hair -follicle, skin, bone, saliva, sper m etc.), from an individual show the same degree of polymorphism, they become very useful identification tool in forensic applications.'

Polymorphism at the DNA sequence level serves as the basis for which of the following applications mentioned in the text?

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Explanation

The NCERT text explicitly states: 'As polymorphism in DNA sequence is the basis of genetic mapping of human genome as well as of DNA fingerprinting...'

In the process of DNA fingerprinting using Southern blot hybridization, what is the role of the VNTR probe?

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Explanation

The text mentions 'hybridisation using labelled VNTR probe', indicating its role in binding to complementary sequences to allow for detection.

A schematic representation of DNA fingerprinting (Figure 5.16) shows the banding pattern of DNA from a crime scene matching with individual B. This implies:

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Explanation

Figure 5.16 caption states: 'It is clear that the banding pattern of DNA from crime scene matches with individual B, and not with A.' This match indicates individual B's DNA is consistent with the crime scene sample, making them a suspect or the origin of the sample.

Why is DNA fingerprinting considered a 'very quick way' to compare DNA sequences of individuals, compared to sequencing the entire genome?

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Explanation

The text explains: 'sequencing the DNA every time would be a daunting and expensive task... DNA fingerprinting is a very quick way to compare the DNA sequences of any two individuals' by identifying 'differences in some specific regions in DNA sequence called as repetitive DNA, because in these sequences, a small stretch of DNA is repeated many times.'

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