Molecular Basis of Inheritance MCQs for NEET — Botany Questions with Answers

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NEET 2024

Hind II always cuts DNA molecules at a particular point called recognition sequence and it consists of:

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Explanation

Hind II recognition sequence is 6 bp (GTY↓RAC).

NEET 2024

A transcription unit in DNA is defined primarily by the three regions in DNA and these are with respect to upstream and down stream end:

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Explanation

A transcription unit = promoter (upstream) — structural gene — terminator (downstream).

NEET 2024

The DNA present in chloroplast is:

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Explanation

Chloroplast (and mitochondrial) DNA is circular and double-stranded — like prokaryotic DNA.

NEET 2024

Which of the following statement is correct regarding the process of replication in E. coli?

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Explanation

All known DNA polymerases extend the new strand strictly in the $5' \to 3'$ direction.

NEET 2024

Match List I with List II.

List I List II
A. Frederick Griffith I. Genetic code
B. Francois Jacob & Jacque Monod II. Semi-conservative mode of DNA replication
C. Har Gobind Khorana III. Transformation
D. Meselson & Stahl IV. Lac operon

Choose the correct answer from the options given below:

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Explanation

Griffith — transformation; Jacob & Monod — lac operon; Khorana — genetic code; Meselson & Stahl — semi-conservative replication.

NEET 2025

Given below are two statements:

Statement I: In the RNA world, RNA is considered the first genetic material evolved to carry out essential life processes. RNA acts as a genetic material and also as a catalyst for some important biochemical reactions in living systems. Being reactive, RNA is unstable.

Statement II: DNA evolved from RNA and is a more stable genetic material. Its double helical strands being complementary, resist changes by evolving repairing mechanism.

In the light of the above statements, choose the most appropriate answer:

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Explanation

Both statements correctly describe the RNA-world hypothesis and the subsequent evolution of the more stable, self-repairing DNA.

NEET 2025

Which chromosome in the human genome has the highest number of genes?

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Explanation

Chromosome 1, the largest human chromosome, carries the maximum number of genes (~2968); the Y chromosome has the fewest.

NEET 2025

Given below are two statements:

Statement I: Transfer RNAs and ribosomal RNA do not interact with mRNA.

Statement II: RNA interference (RNAi) takes place in all eukaryotic organisms as a method of cellular defence.

In the light of the above statements, choose the most appropriate answer:

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Explanation

tRNA and rRNA do interact with mRNA during translation, so Statement I is incorrect. RNAi is a conserved cellular defence in eukaryotes, so Statement II is correct.

NEET 2025

Which of the following are the post-transcriptional events in a eukaryotic cell? A. Transport of pre-mRNA to cytoplasm prior to splicing. B. Removal of introns and joining of exons. C. Addition of methyl group at 5' end of hnRNA. D. Addition of adenine residues at 3' end of hnRNA. E. Base pairing of two complementary RNAs. Choose the correct answer:

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Explanation

Post-transcriptional processing of hnRNA = splicing (B), 5′ capping (C) and 3′ poly-A tailing (D). pre-mRNA is processed before, not after, leaving the nucleus (A wrong); E is unrelated.

NEET 2025

Match List I with List II:

List-I — A. Alfred Hershey and Martha Chase, B. Euchromatin, C. Frederick Griffith, D. Heterochromatin

List-II — I. Streptococcus pneumoniae, II. Densely packed and dark-stained, III. Loosely packed and light-stained, IV. DNA as genetic material confirmation

Choose the correct answer:

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Explanation

Hershey & Chase → confirmed DNA as genetic material (IV); Euchromatin → loosely packed, light-stained (III); Griffith → Streptococcus pneumoniae transformation (I); Heterochromatin → densely packed, dark-stained (II).

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