Practice free Biotechnology and its Applications (Zoology) NEET multiple-choice questions online with instant answers and detailed explanations. No login required.
Transgenic plants engineered with RNAi technology against nematodes are described as being protected. This protection is a result of:
The explanation indicates that the 'silencing of the specific mRNA of the nematode' leads to its inability to survive. The transgenic plant therefore got itself protected from the parasite.
Which of the following describes the primary goal of creating transgenic animal models for the study of disease?
According to the NCERT text, 'Many transgenic animals are designed to increase our understanding of how genes contribute to the development of disease. These are specially made to serve as models for human diseases so that investigation of new treatments for diseases is made possible.'
Rosie, the first transgenic cow, was renowned for producing milk enriched with which human protein?
The NCERT states, 'In 1997, the first transgenic cow, Rosie, produced human protein-enriched milk (2.4 grams per litre). The milk contained the human alpha-lactalbumin and was nutritionally a more balanced product for human babies than natural cow-milk.'
Transgenic animals are made more sensitive to toxic substances for which specific application?
The text mentions, 'Transgenic animals are made that carry genes which make them more sensitive to toxic substances than non-transgenic animals. They are then exposed to the toxic substances and the effects studied. Toxicity testing in such animals will allow us to obtain results in less time.'
For which of the following human diseases are transgenic models currently available, according to the NCERT text?
The NCERT states, 'Today transgenic models exist for many human diseases such as cancer, cystic fibrosis, rheumatoid arthritis and Alzheimer’s.'
The production of human $\alpha$-1-antitrypsin by transgenic animals is an effort to treat which human ailment?
As per the text, 'Transgenic animals that produce useful biological products can be created by the introduction of the portion of DNA (or genes) which codes for a particular product such as human protein ($\alpha$-1-antitrypsin) used to treat emphysema.'
Which of the following is NOT a common reason for producing transgenic animals?
The NCERT outlines reasons such as 'Normal physiology and development', 'Study of disease', 'Biological products', 'Vaccine safety', and 'Chemical safety testing'. Increasing genetic diversity in a wild population is not listed as a direct goal for producing transgenic animals.
In the context of vaccine safety testing, which animal could potentially be replaced by transgenic mice if the latter are found reliable?
The text states, 'Transgenic mice are being used to test the safety of the polio vaccine. If successful and found to be reliable, they could replace the use of monkeys to test the safety of batches of the vaccine.'
Ethical issues surrounding genetic modification of organisms primarily arise due to:
The NCERT mentions, 'Genetic modification of organisms can have unpredictable results when such organisms are introduced into the ecosystem.' It also highlights the need for regulation to evaluate the 'morality of all human activities that might help or harm living organisms.'
The primary objective of developing transgenic animals for 'Normal physiology and development' studies is to:
The NCERT elaborates, 'Transgenic animals can be specifically designed to allow the study of how genes are regulated, and how they affect the normal functions of the body and its development, e.g., study of complex factors involved in growth such as insulin-like growth factor.'
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