Practice free Biotechnology and its Applications (Zoology) NEET multiple-choice questions online with instant answers and detailed explanations. No login required.
Which of the following represents a principle of gene therapy as described in the provided text?
The text states, 'It does so by replacing a defective mutant allele with a functional one or gene targeting which involves gene amplification.' Option o2 directly reflects this principle.
The use of viruses as vectors in gene therapy leverages their natural ability to:
The text specifies, 'Viruses that attack their hosts and introduce their genetic material into the host cell as part of their replication cycle are used as vectors to transfer healthy genes or more recently portions of genes.' This highlights their natural gene delivery mechanism.
Which of the following human proteins is mentioned as being produced by transgenic animals to treat emphysema?
According to the NCERT text, 'Transgenic animals that produce useful biological products can be created by the introduction of the portion of DNA (or genes) which codes for a particular product such as human protein ($\alpha$-1-antitrypsin) used to treat emphysema.'
The first transgenic cow, Rosie, produced milk enriched with which human protein?
The NCERT text states, 'In 1997, the first transgenic cow, Rosie, produced human protein-enriched milk (2.4 grams per litre). The milk contained the human alpha-lactalbumin and was nutritionally a more balanced product for human babies than natural cow-milk.'
Which of the following diseases are 'transgenic models' mentioned as existing for in the provided text?
The NCERT text states, 'Today transgenic models exist for many human diseases such as cancer, cystic fibrosis, rheumatoid arthritis and Alzheimer’s.'
What was a key advantage of Rosie's milk for human babies compared to natural cow's milk?
The NCERT text highlights that Rosie's milk, containing human alpha-lactalbumin, 'was nutritionally a more balanced product for human babies than natural cow-milk'.
The study of complex factors involved in growth, such as insulin-like growth factor, by altering gene formation, falls under which category of transgenic animal application?
The NCERT text specifies, '(i) Normal physiology and development: Transgenic animals can be specifically designed to allow the study of how genes are regulated, and how they affect the normal functions of the body and its development, e.g., study of complex factors involved in growth such as insulin-like growth factor.'
What is the primary reason for ethical concerns regarding the genetic modification of organisms, as mentioned in the text?
The NCERT text states, 'Genetic modification of organisms can have unpredictable results when such organisms are introduced into the ecosystem.' This is mentioned under 'ETHICAL ISSUES'.
Transgenic mice are being developed to test the safety of which specific vaccine mentioned in the text?
The NCERT text explicitly states, 'Transgenic mice are being used to test the safety of the polio vaccine.'
For which genetic disorder are attempts being made to treat using biological products produced by transgenic animals, besides emphysema?
The NCERT text mentions, 'Similar attempts are being made for treatment of phenylketonuria (PKU) and cystic fibrosis' in the context of producing biological products from transgenic animals.
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